pentobarbital will minimize the extent or outcome of ethotoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Observe.pentobarbital will minimize the level or outcome of tramadol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Reduced AUC of tramadol as well as Energetic metabolite (O-desmethylt